disease (also known as Parkinson disease, Parkinson's, idiopathic
Parkinsonism, primary Parkinsonism, PD, or paralysis agitans) is a
degenerative disorder of the central nervous system. The motor
symptoms of Parkinson's disease result from the death of
dopamine-generating cells in the substantia nigra, a region of the
midbrain; the cause of this cell death is unknown. Early in the
course of the disease, the most obvious symptoms are movement
related; these include shaking, rigidity, slowness of movement and
difficulty with walking and gait. Later, cognitive and behavioral
problems may arise, with dementia commonly occurring in the
advanced stages of the disease. Other symptoms include sensory,
sleep and emotional problems. PD is more common in the elderly,
with most cases occurring after the age of 50.
Disease starts insidiously, may be in the upper limb of one side and then spreading. Loss of associated movements is often the first indication.
symptoms include: anxiety, insecurity, and stress,
confusion, memory loss, and dementia (more common in elderly
individuals), constipation, depression, male erectile
Parkinson's disease is caused by a lack of dopamine due to the loss of dopamine-producing cells in the substantia nigra.